Indlela yokusebenza ye-chondroitin sulfate (CS)
1. ukuncedisa iproteoglycans ukulungisa i-cartilage edibeneyo.
2. Unefuthe elinamandla le-hydration kwaye unako ukutsala amanzi kwiimolekyuli zeproteoglycan, okwenza i-cartilage ibe nkulu njengesiponji, inika amanzi kunye nezondlo kwi-cartilage, iphucula i-metabolism ye-cartilage, ngaloo ndlela idlala indima yokutshatyalaliswa kunye nokuthambisa, kwaye waziwa ngokuba “yimagnethi yolwelo”.
3. Ukukhuselwa kwe-cartilage ngokuvimbela isenzo se-enzyme "esichitha i-cartilage" (umzekelo, i-collagenase, i-histoproteinase).
4. Ukunciphisa intlungu, ukuvuvukala kunye nokuqina kunye nokuphucula umsebenzi wokuhamba ngokubambisana.
I-Chondroitin sulfate (CS) idibene ne-glucosamine (GS)
● I-Chondroitin sulfate (CS) ikhawuleza inkqubo yokungena kwe-glucosamine sulfate kwi-joint, kwaye ukudibanisa kwezi zibini kusebenza ngakumbi ekulungiseni i-cartilage edibeneyo kunye nokubuyisela i-cartilage eyonakalisiweyo.
● Ukudibanisa kwe-GS kunye ne-CS kunokuphucula ukuvinjelwa kokuveliswa kweentlobo ezahlukeneyo zokuvuvukala kunye ne-oxygen free radicals kwizicubu ezihlangeneyo, ukuvimbela umsebenzi we-metalloproteinase kunye nokuzinzisa i-lysosomal membranes, ngaloo ndlela ukubonelela ngemiphumo echasayo kunye ne-analgesic. Ukudibanisa kwezi zibini kunokukhuthaza ukuhlanganiswa kweproteoglycans kunye ne-collagen kwi-articular cartilage tissue, ukugcina ukuzinza kwe-cartilage extracellular matrix, kunye nokudlala indima engathanga ngqo ekupheliseni ukuvuvukala kunye nokunciphisa intlungu.
● Ukuqwalaselwa kweekliniki kwakhona kubonisa ukuba unyango lwezigulane ezilinganisiweyo kunye ezinzima, umphumo odibeneyo we-GS kunye ne-CS uphezulu kuneyechiza elilodwa, elinokunciphisa ngempumelelo intlungu yezigulane.
Ixesha lokuposa: Nov-19-2022