I-Tremela fungus i-polysaccharides inokunciphisa kakhulu amanqanaba e-glucose yegazi kwi-diabetic miceus ebangelwa yi-tetraoxopyrimidine kunye ne-streptochlorin-induced diabetic mice, ukwandisa amanqanaba e-insulin e-serum, kunye nokunciphisa ukungenisa kwamanzi kwiigundane zesifo sikashukela. I-receptor isebenze yi-mouse peroxisome proliferative factor yi-γ (i-peroxisome proliferators-activated receptor-γ，PPAR-γ) umlawuli oyintloko wesenzo se-insulin, kunye nokubonakaliswa kwe-PPAR-γmRNA kunye ne-plasma PPAR-γ iprotheni yanda kakhulu xa iigundane zondliwa. nge tremela extracellular polysaccharides iintsuku ezingama-52. Oku kuphakamisa ukuba i-tremella polysaccharides inokunciphisa iswekile yegazi kunye nokuphucula i-insulin sensitivity ngokulawula i-PPAR-γ-mediated lipid metabolism.
I-Tremela polysaccharides inciphisa i-lipids yegazi ngokuthintela ukufunxwa kwe-lipids emathunjini eempuku kunye neempuku, kwaye indlela inokuba kungenxa yokuba i-polysaccharides ye-tremella fungus igcwele amaqela e-hydroxyl, amaqela e-carboxyl kunye namaqela e-amino, ane-hydrophilicity eyomeleleyo kunye ne-adsorb lipids kunye cholesterol ukuthintela ukufunxwa lipids. Ngelo xesha, i-polysaccharide yesiliva ye-fungus inokudibanisa ne-bile acid, ikhuthaze ukukhutshwa kwe-bile acid, ithintele isibindi kunye nokujikeleza kwamathumbu, ukwenzela ukuba i-cholesterol metabolism iqhutywe kakuhle kwicala elinye kwaye inciphise i-lipids yegazi. [1]
[Imbekiselo].
[1] WEI Guo-Zhi, LI Guo-Guang, JIN Mei-Hong. Inkqubela phambili yophando kwi-polysaccharides ye-fungus yesilivere [J]. Iincasa kunye neZithambiso, i-2008 (2): 33-35.
Ixesha lokuposa: Oct-20-2022